Figures – The H-PFC pathway.
(A) Drawling of the human brain from the midsagittal perspective showing the hippocampus (yellow) amygdala (lavender), and mPFC (light blue).
(B) Schematic showing the general connectivity of the hippocampus, amygdala and PFC in the rat, with the H-PFC pathway projecting from the subiculum and ventral CA1 region of the hippocampus to the PFC. The neuronal connections are unidirectional and glutamatergic. The ventral hippocampus also has bidirectional connections with the amygdala, and the amygdala has bidirectional connections with the PFC.